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Article

Natural Alternatives to Ibuprofen

Tuesday, April 4th 2023 10:00am 5 min read
Dr. Jessica Peatross dr.jess.md @drjessmd

Hospitalist & top functional MD who gets to the root cause. Stealth infection & environmental toxicity keynote speaker.

When pain strikes, many of us instinctively reach for a bottle of ibuprofen, an over-the-counter nonsteroidal anti-inflammatory drug (NSAID) that can help to relieve aches and pains, reduce fever, and alleviate inflammation. However, ibuprofen is not without its risks, and long-term or excessive use can cause a range of side effects, including gastrointestinal problems, kidney damage, and increased risk of heart attack and stroke. Furthermore, recent studies have suggested that ibuprofen may increase the risk of cardiac arrest, a sudden and often fatal condition in which the heart stops beating.

Fortunately, there are a number of natural alternatives to ibuprofen that may help to reduce pain and inflammation without the same risk of side effects. Here are six options to consider:

Arnica

Arnica is a plant that grows in mountainous regions and has been used for centuries as a natural remedy for pain and inflammation. Studies have shown that arnica can be effective for reducing pain and stiffness in people with osteoarthritis, as well as for reducing inflammation after surgery. Arnica can be applied topically as a cream, gel, or ointment, or taken orally in homeopathic preparations. It’s important to note, however, that arnica should not be taken internally in large amounts, as it can be toxic.

Ginger

Ginger is a spice with potent anti-inflammatory and pain-relieving properties. It contains compounds called gingerols and shogaols that have been shown to reduce pain and inflammation in people with osteoarthritis, menstrual pain, and other conditions. Ginger can be taken in a variety of forms, including fresh or dried root, tea, capsules, or as an oil or cream. While ginger is generally safe and well-tolerated, it can cause mild side effects such as heartburn, diarrhea, and skin irritation in some people.

Turmeric

Turmeric is a bright yellow spice that is commonly used in Indian and Middle Eastern cuisine. It contains a compound called curcumin, which has powerful anti-inflammatory and antioxidant properties. Studies have shown that curcumin can be effective for reducing pain and inflammation in people with osteoarthritis, rheumatoid arthritis, and other conditions. Turmeric can be taken as a spice in cooking, or in supplement form as a capsule or tablet. While turmeric is generally safe and well-tolerated, it can cause stomach upset and other side effects in some people.

Thyme

Thyme is an herb that is commonly used in cooking, and it also has medicinal properties. It contains compounds called thymol and carvacrol, which have been shown to have anti-inflammatory and pain-relieving effects. Studies have found that thyme can be effective for reducing pain and inflammation in people with menstrual cramps, as well as for reducing coughing and other symptoms of respiratory infections. Thyme can be taken as a tea, tincture, or inhaled as an essential oil. However, thyme should not be taken in large amounts or used for extended periods of time, as it can be toxic.

Omega-3 fatty acids

Omega-3 fatty acids are a type of healthy fat that are found in certain foods, such as fatty fish, nuts, and seeds. They have been shown to have anti-inflammatory properties and can help to reduce pain and inflammation in people with a range of conditions, including rheumatoid arthritis and menstrual pain. Omega-3 supplements are also available in the form of fish oil or krill oil capsules. While omega-3s are generally safe and well-tolerated, they can cause mild side effects such as fishy burps and upset stomach in some people.

Cinnamon

Cinnamon is a spice that is commonly used in baking and cooking, and it also has anti-inflammatory and pain-relieving properties. It contains compounds called cinnamaldehyde and cinnamic acid, which have been shown to have antioxidant and anti-inflammatory effects. Studies have found that cinnamon can be effective for reducing pain and inflammation in people with conditions such as osteoarthritis, menstrual pain, and diabetes. Cinnamon can be taken as a spice in cooking, or as a supplement in capsule or tablet form. While cinnamon is generally safe and well-tolerated, it can cause mild side effects such as mouth irritation and allergic reactions in some people.

The Risks of using ibuprofen

Now let’s turn to the potential risks of ibuprofen. While ibuprofen is generally considered safe when taken as directed, long-term or excessive use can increase the risk of a range of side effects. For example, ibuprofen can cause gastrointestinal problems such as stomach ulcers, bleeding, and perforation. It can also cause kidney damage, particularly in people who already have kidney problems. In addition, recent studies have suggested that ibuprofen may increase the risk of cardiac arrest, a sudden and often fatal condition in which the heart stops beating.

According to a study published in the European Heart Journal in 2017, taking high doses of ibuprofen (over 1,200 mg per day) was associated with a 31% increased risk of cardiac arrest. The study analyzed data from nearly 29,000 cases of cardiac arrest that occurred in Denmark between 2001 and 2010, and found that 3% of the cases were attributed to NSAID use, with ibuprofen being the most commonly used NSAID. The risk was particularly high in people with pre-existing heart conditions or other risk factors for heart disease.

Another study, published in the Journal of the American College of Cardiology in 2018, found that NSAID use was associated with a higher risk of major adverse cardiovascular events, such as heart attack and stroke. The study analyzed data from over 446,000 people who were prescribed NSAIDs between 2008 and 2015, and found that the risk increased with higher doses and longer duration of use.

It’s important to note, however, that the risk of cardiac arrest or other cardiovascular events associated with ibuprofen use is still relatively low, particularly in healthy individuals who take the medication as directed. According to a review of studies published in the British Journal of Clinical Pharmacology in 2018, the overall risk of NSAID-associated cardiac events was estimated to be around 0.2%, or 2 cases per 1,000 people treated with NSAIDs for one year.

Final thoughts

In conclusion, while ibuprofen can be an effective medication for reducing pain and inflammation, it is not without its risks. Natural alternatives such as arnica, ginger, turmeric, thyme, omega-3s, and cinnamon may be a safer option for some individuals, particularly those who have a history of gastrointestinal or kidney problems, or who are at risk for cardiovascular disease. As always, it’s important to consult with a healthcare provider before starting any new medication or supplement, to ensure that it is safe and appropriate for your individual needs.

References:

European Medicines Agency. Ibuprofen and risk of cardiovascular side effects. Available at: https://www.ema.europa.eu/en/documents/referral/ibuprofen-article-31-referral-assessment-report_en.pdf. Accessed January 24, 2023.

Gagnier JJ, van Tulder MW, Berman B, et al. Herbal medicine for low back pain: a Cochrane review. Spine (Phila Pa 1976) 2016;41(2):116-33.

Kuptniratsaikul V, Thanakhumtorn S, Chinswangwatanakul P, et al. Efficacy and safety of Curcuma domestica extracts in patients with knee osteoarthritis. J Altern Complement Med 2009;15(8):891-7.

Langmead L, Feakins RM, Goldthorpe S, et al. Randomized, double-blind, placebo-controlled trial of oral aloe vera gel for active ulcerative colitis. Aliment Pharmacol Ther 2004;19(7):739-47.

Razzaque MS. The dualistic role of vitamin D in vascular calcifications. Kidney Int 2011;79(7):708-14.

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