Our bodies are complex examples of biochemistry. Each system works diligently with the others to help you live, breathe, and perform your daily functions at the most optimum level possible.
A key example of this is methylation. This process is extremely vital to how we function, although most of us haven’t heard of it. Let’s take a deeper look at this critical process, what happens when the process malfunctions, and how to naturally support methylation in your body.
What is methylation?
Methylation is a biochemical process that your body relies on to keep you healthy and thriving. This process happens close to 1 billion times every second and controls your ability to detox and in turn, lower inflammation, produce neurotransmitters and protect your DNA. Every cell of your body depends on methylation, which is why if methylation is not functioning optimally, you’re bound to have a few health problems.
What happens with poor methylation?
Poor methylation has been linked to:
- Autoimmune conditions
- Chronic inflammation
- Fatigue
- Heart disease
- Hormone imbalances
- Anxiety
- Depression
There are many causes of poor methylation, one of which is the MTHFR gene mutation. The function of the MTHFR enzyme is to convert folic acid into folate which is the fuel for methylation. It is estimated that those with MTHFR gene mutations make 70% less methyl-folate than someone without the mutation.
There are two main MTHFR mutations – A1298C and C677T. Mutations of A1298C are linked to mood disorders since it plays a vital role in neurotransmitter function. When C677T is altered, it can lead to high levels of inflammatory homocysteine, which is linked to autoimmune conditions and heart disease.
Mutations in the MTR and MTRR genes can also contribute to less than optimal methylation. These genes help produce B12 which is a methyl donor. Those with this mutation use B12 more quickly than their body can produce it. Higher B12 intake is necessary, often with supplementation, to make sure you are getting the amount your body needs.
Close to 40% of the world’s population has an MTHFR genetic mutation, although few of these people realize it. Genetic testing helps determine if you have any of these mutations that are hindering the methylation process. This is a vital step in taking action on your health in order to reduce your risk for preventable chronic diseases that are triggered by various environmental factors. These factors include diet, microbiome dysfunction, stress, and exposure to environmental toxins among others. Methylation helps protect our bodies from these detrimental factors.
Natural supports for methylation
Even if you have a genetic mutation, you can mitigate the health consequences. You have many choices for natural supports that help methylation and detox pathways throughout your body.
Support detoxification
Certain herbs and spices have powerful detoxification properties including cilantro, parsley, turmeric, and dandelion root. These are easy to add into recipes and can help you detox from heavy metals and other chemicals. Milk thistle is also a great choice as it helps support your body’s largest detoxification organ – your liver.
Switch to clean products
The more toxins you are exposed to on a daily basis can take a toll on your detoxification pathways. Lessen the load on your methylation process by switching your cleaning, beauty, and everyday products to clean, non-toxic versions.
Incorporate superfood medicines
Green leafy vegetables such as spinach, kale, and okra, along with grass-fed organ meats are loaded with B vitamins which are the required fuel for methylation.
Eat more sulfur-rich foods
Foods high in sulfur like cabbage, cauliflower, broccoli, onions, garlic, and mushrooms also help to support methylation.
De-stress
If you needed another reason to manage your stress levels, did you know that stress can actually change the methylation of your DNA and alter the activity of certain genes? Try managing stress by incorporating a daily ritual of mindfulness, meditation, or breathwork to help you stay calm throughout your day.
Final thoughts
While these methylation tips are helpful, if you have a genetic mutation, you may need extra support with supplements
Since B vitamins act as fuel for your methylation pathways, they are frequently necessary to enable optimum functioning. However, not all supplements are equal to each other. In fact, folic acid in particular can be toxic for anyone with an MTHFR mutation. Instead, look for natural folate and activated forms of B vitamins.